Mometasone furoate is a synthetic corticosteroid belonging to the class of medications known as glucocorticoids. It is used topically in the form of creams, lotions, and ointments to treat various skin conditions like eczema, psoriasis, dermatitis and allergic skin reactions.
Mechanism of Action
Glucocorticoids like Mometasone Furoate exert their anti-inflammatory and immunosuppressive effects by binding to intracellular glucocorticoid receptors. This leads to decreased production of inflammatory mediators like prostaglandins, leukotrienes, histamines and cytokines. They also inhibit the migration of leukocytes and lymphocytes to the site of inflammation thereby reducing redness, itching and swelling.
Indications
Mometasone furoate is approved by the FDA for treatment of inflammatory skin diseases which includes:
– Atopic dermatitis or eczema: It effectively controls itching, inflammation and prevents flare-ups of eczema when applied topically.
– Psoriasis: As a steroid cream or ointment, it reduces scaling, redness and plaques associated with psoriasis.
– Contact dermatitis: It provides relief from itching and irritation caused by allergic skin reactions to various allergens.
– Seborrheic dermatitis: Commonly known as dandruff, it can control flaky, red lesions on the scalp caused by this condition.
– Other dermatoses: It is also used for conditions like lichen simplex chronicus, discoid lupus erythematosus, perioral dermatitis and hemorrhoids.
Dosage and Administration
Mometasone furoate is available in cream, ointment, lotion and solution formulations of varying strengths between 0.1% to 0.2%. The recommended application frequency depends on the specific condition being treated and its severity. It is usually applied sparingly to the affected areas of skin 1-4 times daily until signs and symptoms improve. Hands should be washed after application.
Safety and Side effects
Being a topical steroid, mometasone furoate is generally well-tolerated with minimal systemic absorption and side effects. Common local side effects may include burning, stinging, itching, dryness and skin atrophy with prolonged use. To minimize risks, it should not be used under occlusion or tight clothing and the specified dosage and duration should not be exceeded.
In mometasone furoate is an effective topical corticosteroid therapy for treatment of inflammatory skin diseases due to its potent anti-inflammatory and immunosuppressive actions. When used as directed under medical supervision, it provides fast relief from skin symptoms with a low risk of adverse effects. It remains an important therapeutic option for management of many dermatological conditions.
Get More Insights – Mometasone Furoate
Get This Report in Japanese Language –モメタゾンフロエート市場
Get This Report in Korean Language –모메타손 푸로에이트 시장
About Author:
Vaagisha brings over three years of expertise as a content editor in the market research domain. Originally a creative writer, she discovered her passion for editing, combining her flair for writing with a meticulous eye for detail. Her ability to craft and refine compelling content makes her an invaluable asset in delivering polished and engaging write-ups.
(LinkedIn: https://www.linkedin.com/in/vaagisha-singh-8080b91)