Animal models are living non-human organisms that are used in medical and scientific research and investigations for studying human disease and enhancing treatment options. Animal models provide invaluable insights into human biology and disease progression that cannot be gained by other means. They help researchers gain a better understanding of how the human body functions under both normal and disease conditions.
The necessity for Animal Model Market Demand has increased significantly over the years as the pharmaceutical industry seeks animal-based preclinical studies for drug safety and efficacy testing before human clinical trials. Animal models provide a safe and ethical way to study human health and test potential medications without directly involving human participants initially. Some key advantages of animal models include their anatomical and physiological similarities to humans, ability to monitor disease progression over time and analyze treatment response.
The Global Animal Model Market was valued at US$ 1,577.30 Mn in 2021 and is forecast to reach a value of US$ 2,394.30 Mn by 2028 at a CAGR of 6.0% between 2022 and 2028.
Key Takeaways
Key players operating in the animal model market include Charles River Laboratories, The Jackson Laboratory, Taconic Biosciences, Envigo, and GenOway. These players are focusing on expanding their animal model portfolios and enhancing research capacities to cater to growing demand.
The demand for animal models is increasing considerably owing to rising research activities in disease pathology, drug discovery and development, and toxicity testing. Animal models are increasingly being used to study complex human diseases like cancer, neurological disorders, cardiac ailments and develop novel treatments. Furthermore, the COVID-19 pandemic has accelerated research into coronaviruses using animal models.
Advancements in genetic engineering technologies like CRISPR/Cas9 have enabled the development of genetically modified animal models that more closely mimic human diseases and are valuable tools for biomedical research. Customized animal models have improved predictive value for preclinical drug testing and evaluating disease progression and treatment responses.
Market Trends
The growing preference for humanized animal models: There is increasing focus on developing humanized animal models like humanized mice that have human tissues, cells, or genes within the animal. These closely mimic human biology and disease conditions.
Adoption of cross-species organoid technology: Organoids are 3D cell culture models of organs grown from stem cells. They better represent complex human organ structure and physiology. Cross-species organoids using human and animal cells are gaining traction.
Market Opportunities
Increasing research into rare and orphan diseases: Animal models can help advance understanding of rare diseases and expedite development of orphan drugs to treat conditions with small patient populations.
Rise of animal models in toxicity testing: Regulatory mandates are promoting increased use of animal models for chemical and drug safety evaluation prior to human exposure to minimize health risks.
Impact of COVID-19 on Animal Model Market Growth
The COVID-19 pandemic has significantly impacted the growth of the animal model market. Initially during the outbreak in early 2020, research activities involving animal models declined significantly as researchers focused their efforts on COVID-19 related projects. Several non-essential research facilities were also temporarily shut down to avoid the spread of the virus. This led to reduced demand for animal models during that period. However, as the pandemic progressed, the use of animal models increased substantially to test vaccines and therapies for COVID-19. Several pharmaceutical companies and research institutes used mouse, monkey and other animal models to screen vaccine candidates and study virus pathogenesis. Governments and funding agencies also increased funding for COVID-19 related research using animal models. This boosted the animal model market in late 2020 and 2021. Even now, researchers continue to rely on animal models to further study virus variants and long term effects of the virus. Although the pandemic disrupted market growth initially, in the long run it has opened newer opportunities for development and use of animal models for COVID-19 research. The demand for certain types of animal models like non-human primates has outpaced supply due to the pandemic. This trend is likely to continue as new variants emerge and long term studies get conducted.
North America Region Dominates Animal Model Market in Terms of Value
The North America region accounts for the largest share of the global animal model market in terms of value. This is primarily due to strong support for biomedical research from both public and private funding organizations in countries like the United States. Presence of top pharmaceutical companies and contract research organizations who rely heavily on animal models for drug development and toxicity studies also drives market growth. High healthcare spending and advanced research infrastructure further boosts the adoption of animal models in the region. The United States alone contributes over 40% of the global market value owing to the large number of major companies located in the country. Europe is the second largest regional market supported by funding from the European Commission for academic research using animal models.
Asia Pacific Emerges as the Fastest Growing Region in Animal Model Market
The Asia Pacific region has emerged as the fastest growing regional market for animal models globally. This is due to increasing biomedical research expenditure especially in China and India. Governments of these countries are focused on developing local life science capabilities through initiatives to establish new research parks and institutions. This is translating to rising demand for animal models from both public and private sector. Rapid expansion of pharmaceutical and biotech industry in the region coupled with low costs have attracted several multinational companies to set up manufacturing and R&D centers. In addition, contract research organizations are shifting focus towards Asia pacific to leverage low costs. All these factors are fueling strong growth in demand for animal models in Asia Pacific region. China especially is projected to surpass major Western markets due to aggressive investments in building a robust innovation ecosystem.
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